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AI x Science Postdoctoral Fellows collaborate across disciplines
Sibe-by-side portraits of Brynn Sherman, on left, and Kieran Murphy, right.

Penn’s AI x Science Postdoctoral Fellows Program is breaking down traditional scientific boundaries by integrating artificial intelligence across diverse research fields. Less than a year in, the program is already paying dividends in the form of new collaborations and research publications for inaugural fellows like Brynn Sherman (left) of the School of Arts & Sciences and Kieran Murphy (right) of the School of Engineering and Applied Science.

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AI x Science Postdoctoral Fellows collaborate across disciplines

The new fellowship program, offered through the School of Arts & Sciences and the School of Engineering and Applied Science, offers mentorship and peer engagement opportunities.

5 min. read

New class of materials passively harvest water from air
A water droplet reflecting the color spectrum.

Image: MamiGibbs via Getty Images

New class of materials passively harvest water from air

Researchers at Penn Engineering have discovered a new class of nanostructured materials that can pull water from the air, which could enable new ways to collect water in arid regions and devices that cool electronics or buildings using the power of evaporation.

Melissa Pappas

2 min. read

Unlocking the mechanics of protein misfolding
Artist's interpretation of prion mechanics.

Mathieu Ouellet

Unlocking the mechanics of protein misfolding

An interdisciplinary team led by School of Engineering and Applied Science’s Lee C. Bassett and Dani Bassett, also of the School of Arts & Sciences, have studied the mechanical properties of prions, the mysterious shape-shifting proteins that are infamous for mad cow disease yet essential for yeast survival

5 min. read

Delivering a one-two punch to superbugs to fight infections
Rakesh Krishnan sits at a computer staring at a 3D rendering of a protein.

Researchers led by César de la Fuente of the Perelman School of Medicine have created new peptides that fight hard-to-treat “superbug” infections by punching holes in bacterial cells and stimulating immune cells to signal for more defenders.

(Image: Courtesy of Jianing Bai) 

Delivering a one-two punch to superbugs to fight infections

Penn researchers create mirror-image molecules that both kill pathogens outright and rally the immune system—an advance aimed at the growing crisis of antimicrobial resistance.

3 min. read

Lillian Miller: May grad turned Penn Ph.D.
Lillian Miller and Irina Marinov

Lillian Miller (left) graduated as a chemistry and environmental scieces double major in May. This summer, she returns to begin her graduate training in Irina Marinov’s (right), where researchers use big data and computational techniques to make better climate models.

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Lillian Miller: May grad turned Penn Ph.D.

Lillian Miller, a May graduate from the College, will begin graduate studies in the laboratory of Irina Marinov this summer, where she is leveraging big data to tackle ocean and climate-focused research.

5 min. read

Penn Engineers examine the fracture mechanics of 3D graphene structures

Penn Engineers examine the fracture mechanics of 3D graphene structures

A new study from teams in the labs of Penn Engineering’s Ottman Tertuliano and Robert Carpick describes a new, 3D auto-kirigami deformation of graphene, one of the strongest materials known to science, and how the process could be used to transform 2D graphene into 3D structures.

National Academy of Sciences elects four from Penn
Four headshots of Penn Faculty. Top left tile clockwise: Mark Devlin, Katalin Karikó, E. John Wherry III, and Virginia M.Y. Lee

Four faculty have been elected to the National Academy of Sciences in recognition of their innovative contributions to original scientific research. The newly honored scholars are Mark Devlin (top left) from the School of Arts & Sciences and Katalin Karikó (top right), Virginia M.Y. Lee (bottom left), and E. John Wherry III (bottom right) from the Perelman School of Medicine.

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National Academy of Sciences elects four from Penn

The newly elected members, recognized for their innovative contributions to original research, are Mark Devlin of the School of Arts & Sciences and Katalin Karikó, Virginia Lee, and E. John Wherry III of the Perelman School of Medicine.

3 min. read

Armoring CAR T cells to take on cancer
3D visualization showing a reddish-blue tumor mass with internal vasculature, surrounded by blue CAR T cells and small extracellular vesicles against a dark background.

Wei Guo of the School of Arts & Sciences and colleagues from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science have teamed up to uncover how solid tumors’ complicated microenvironments can manipulate cancer-fighting CAR T cells through extracellular vesicles, causing the engineered CAR T cells to commit fratricide—essentially turning against each other instead of attacking the cancer.

(Image: iStock / Marcin Klapczynski)

Armoring CAR T cells to take on cancer

Wei Guo of the School of Arts & Sciences and colleagues from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science have uncovered how solid tumors manipulate cancer-fighting CAR T cells through extracellular vesicles, causing the engineered CAR T cells to commit fratricide—essentially turning against each other instead of attacking the cancer.

3 min. read